Improvement of Gene-Edited Immune Cell Manufacturing for Clinical Trials

We are collaborating with multiple labs at UCSF to establish a gene-edited immune cell clinical platform

As immunotherapeutic strategies move toward more complex engineering and multiplexed editing, there is a growing need to optimize the manufacturing of CAR-engineered cells for the clinic. Our laboratory is focused on bolstering the efficiency of CAR T cell enrichment, improving the precision of T cell editing using novel tools developed in the lab. Finally, we are expanding our technologies to other immune cells and are optimizing gene editing protocols and CAR designs for NK cells.

Research Team

Alexis Talbot

Postdoctoral Scholar (2020–2023), Current Position: Assistant Professor, Saint-Louis University Hospital, University of Paris

Allison Rothrock

Research Associate

Chris Chang

MSTP Student

Joseph Muldoon

CRI Irvington Postdoctoral Fellow

Vincent Allain

Postdoctoral Scholar, UCSF / Graduate Student, University of Paris